Bioidentical Hormone Replacement Therapy for Women - Precision Menopause Treatment, Harley Street

Request a call back

Your hormones are not just about symptoms. They are one of the most powerful levers in your biological ageing - and they are measurable, optimisable, and in most cases, correctable.

FEES BOOK ONLINE

Booking:

info@thenaturaldoctor.org

Tel:

020 7224 4622

Hormonal changes can leave you feeling tired, fuzzy-headed, low in energy, or simply out of sync with your body. You may notice weight gain, disrupted sleep, brain fog you’ve started explaining away, or a loss of the drive and confidence that used to come naturally.

These are not signs of weakness or inevitable age. They are precise biological signals – and at The Natural Doctor, we are trained to read them properly.

At The Natural Doctor, our Bioidentical Hormone Replacement Therapy (BHRT) for women offers a completely bespoke, science-led approach to hormone imbalance and better ageing. But we want to be clear about what that means: this is not simply symptom management. Oestrogen, progesterone, testosterone and DHEA are direct regulators of how fast you age at a cellular level – driving mitochondrial biogenesis, protecting telomere length, governing inflammatory tone, and maintaining the cognitive and cardiovascular infrastructure that defines long-term quality of life.

Hormone optimisation is one of the highest-leverage longevity interventions available. The question is whether your healthcare is sophisticated enough to use it precisely – or whether it is simply offering you a standard prescription when what you need is a genuinely personalised strategy.

Make an enquiry

Bioidentical hormones are plant-derived compounds that are structurally identical to the hormones your body produces naturally – body identical hormones in the truest sense. They are more easily recognised and metabolised by the body than synthetic alternatives, and they restore hormonal function without the receptor-binding mismatches that make synthetic HRT a less precise tool.

BHRT helps restore optimal levels of key hormones including oestrogen (oestradiol, oestriol), progesterone, testosterone, DHEA, pregnenolone and melatonin. These hormones regulate metabolism, memory, bone density, libido, mood, cardiovascular health, and – critically – the pace of biological ageing itself. Our aim is to restore your hormone levels to where they were at their functional best: nothing more, nothing less.

Learn more

Bioidentical Hormone Replacement Therapy

Conventional hormone replacement therapy (HRT), typically prescribed on the NHS, often relies on synthetic or animal-derived hormones that are not chemically identical to those your body produces. They can achieve symptom control for many women but they are not a precise biological match – and their safety profile differs from bioidentical hormones in ways that matter particularly for long-term use.

Our BHRT uses bioidentical hormones that mirror your body’s own – personalised HRT at its most precise. This is also compounded HRT: prepared by a licensed specialist pharmacist on a named patient basis under the Medicines Act, allowing precise dosing and hormone combinations that standard prescriptions cannot provide. Testing is comprehensive – up to 68 markers – and monitoring is continuous. This is natural HRT as a clinical science, not a shortcut.

The distinction between bioidentical (natural) progesterone and synthetic progestins is particularly important: large prospective studies including the E3N cohort (80,000 women) demonstrate that bioidentical progesterone does not carry the elevated breast cancer risk associated with synthetic progestins. For women choosing long-term hormone support as part of a longevity strategy, this distinction is clinically material.

The recent Precision Longevity research agenda – including the landmark 2023 hallmarks of ageing framework – has confirmed what clinical practice has long suggested: every major sex hormone is a direct regulator of biological ageing. This means hormonal optimisation is not a luxury or a symptom-relief strategy. It is one of the most powerful single interventions available for extending healthspan.

Oestradiol:

Activates PGC-1α – the master regulator of mitochondrial biogenesis – and upregulates telomerase in neural and vascular tissue. Its decline accelerates mitochondrial ageing, cardiovascular risk, and cognitive deterioration simultaneously. The ‘timing hypothesis’ is now well-supported: starting hormone support during the perimenopause window confers cardiovascular and neuroprotective benefits that late initiation does not.

Progesterone:

Reduces the NLRP3 inflammasome (the primary driver of chronic low-grade inflammation in ageing), promotes restorative sleep through allopregnanolone’s GABA-A activity, and supports mitochondrial function in neural tissue. Deficiency relative to oestrogen – even with normal oestrogen levels – accelerates inflammatory ageing and neurodegeneration.

Testosterone for women:

Declines from the early thirties – a decade before oestrogen – producing the fatigue, cognitive dulling, and lean mass loss that is frequently misattributed to stress. Testosterone supports muscle mitochondrial density, SIRT1 activation, and the anabolic signalling that maintains healthspan across both sexes.

DHEA:

The adrenal longevity reservoir, declines linearly from the mid-twenties. It directly activates SIRT1 through AMPK signalling, provides the precursor substrate for downstream sex hormones, and opposes the cortisol excess that drives hippocampal neuronal loss in the brain and immune deterioration in ageing.

Better sleep

After 6 months, 65% of patients reported improved sleep quality

Enhanced mood

After 12 months, over 60% reported enhanced mood and 68% experienced fewer mood swings

Reduced depression and anxiety

After 12 months, 69% saw improvement in depression and 64% reported reduced anxiety

Reduced hot flushes

After 12 months, 75% saw a reduction in hot flushes

Improved cognitive clarity

Patients consistently report resolution of brain fog within the first 8–12 weeks

Fast-track hormonal support, targeted to your core symptoms

Hormone Testing (5 key markers)
Customised BHRT medication – plant-derived, individually compounded
3-month follow-up and retesting
Full administrative support from our clinical team

Get started

Our signature programme — hormonal optimisation as a long-term longevity strategy

Extensive 68-marker blood panel – hormones, inflammation, functional thyroid testing, metabolic health testing, oxidative stress
Customised BHRT medication (may include pregnenolone and longevity nutraceutical support)
Follow-up testing and ongoing medication management
Physician consultation with Dr Eccles or our specialist team
Optional upgrade to Precision Longevity Programme for comprehensive biological age optimisation

Let’s begin

Step 1: Testing

A comprehensive blood panel – either 5 or 68 markers depending on your programme – arranged at a convenient local laboratory or at our practice.

Step 2: Physician Consultation

Your results are reviewed in detail with one of our doctors or a specialist consultant. Your history, symptoms, goals and test data are used to design your individual treatment protocol.

Step 3: Bespoke Prescription

Your compounded HRT medication is prepared by a specialist licensed pharmacist – individually formulated, precisely dosed, and named specifically to you under the Medicines Act.

Step 4: Ongoing Monitoring

Three-month follow-up retesting to assess response and refine your protocol. Annual reviews to maintain and adapt as your biology evolves.

Book your initial testing

This streamlined option focuses on relieving the key symptoms of hormone imbalance.

Initial Essential Menopause blood testing (5 key markers)

£215

Book Now

Initial Essential Menopause consultation with one of our doctors (up to 30 min)

£295

Book Now

Bespoke medication (bioidentical hormones) – typically up to

£80 / per month*

Book Now

Essential Menopause follow-up consultation with one of our doctors (up to 20 min)

£195

Book Now

Follow-up Essential Menopause blood testing

£215

Book Now

Our signature package, designed for women looking to future-proof their wellbeing.

Initial Comprehensive Menopause blood testing (68 markers)

£655

Book Now

Initial Comprehensive Menopause consultation with one of our doctors (up to 45 min)

£375

Book Now

Bespoke medication (bioidentical hormones) – typically up to

£100 / per month*

Book Now

Comprehensive Menopause follow-up consultation with one of our doctors (up to 30 min)

£275

Book Now

Follow-up Comprehensive Menopause blood testing typically

£415 / *

Book Now

*Please note that the medication fees may vary according to the prescription strength prescribed by the doctor

Dr Nyjon Eccles

BSc, MBBS, MRCP, PhD

Founder & Medical Director. Over 25 years' experience in bioidentical hormone therapy, integrative medicine, and precision longevity. One of the UK's most experienced longevity doctors and a pioneer in compounded hormone medicine and mitochondrial medicine.

Is this the same as standard HRT?

No. Conventional HRT typically uses synthetic or animal-derived hormones. Our BHRT uses body identical hormones – plant-derived compounds structurally identical to your own – compounded specifically for you. This is personalised HRT at its most precise. Combined with 27+ years of clinical experience at one of the best BHRT clinics London has to offer, that depth of care is why patients come to us when standard approaches have fallen short.

What is compounded medicine?

Compounded medicines are custom prescriptions prepared by a licensed pharmacist. They allow precise dosing and hormone combinations tailored to your body, regulated under the Medicines Act and prepared to strict quality and safety standards. This named patient basis preparation is fundamental to why our BHRT achieves outcomes that off-the-shelf prescriptions cannot.

Is BHRT safe?

Yes, when properly monitored. Bioidentical hormones are molecularly identical to those produced by your body and are typically better tolerated than synthetic alternatives. Long-term safety data, including the E3N cohort data for bioidentical progesterone specifically, is reassuring for appropriately monitored patients.

What symptoms might indicate I need BHRT?

Hot flushes, brain fog, fatigue, disrupted sleep, low libido, mood changes, weight gain, vaginal dryness and anxiety are among the most common. Many women also come to us proactively – before symptoms become severe – as part of a longevity and better-ageing strategy.

Do I need a GP referral?

No referral is required. Testing and treatment are arranged directly through The Natural Doctor.

Can I be treated outside the UK?

Yes. We work with patients across Europe and support remote consultations.

Whether you’re managing active symptoms or investing proactively in your long-term hormonal health, our personalised BHRT for women is designed around your unique biology — not a standard protocol.

Book your blood testing today and begin your journey toward feeling more like yourself again.

Testimonials

Christine didn’t wait for the symptoms of the menopause to appear before she started tackling them. Having worked in the …

The Advantages of Being Prepared for the Menopause

When Maddy began to experience menopausal symptoms around the time she turned 50, she did what many women in her …

Maddy’s Bioidentical Hormone Therapy Journey

For more information please fill in our contact form or call us on 0207 2244 622, or email us at info@thenaturaldoctor.org

Google Rating

4.8

The Natural Doctor - Breast Health & BHRT Clinic London

4.8

Alice Cutler

16:12 25 Sep 26

Had another great Breast scan at The Natural Doctor. This is my 4th time at the practice and Susie, the clinician, was as lovely and friendly as the previous staff who have performed the scan for me. They all make you feel very at ease and talk you through any concerns you may have. I can't recommend the team and The Natural Doctor practice itself, highly enough.

sally123lilac

09:10 15 Sep 26

I attended the Clinic yesterday for a thermography breast scan.I was greeting by a very courteous receptionist who led me to the waiting room.The scan was carried out by an extremely personable, professional, warm and friendly young woman, who explained the process to me.The scan was carried out quickly (faster than my previous clinic) with up to date scanning equipment.I was then offered a coffee to take away after the scan.Definitely 5 stars. I would use this Clinic again and would highly recommend the Clinic to friends and family.

35 Lukins

13:12 12 Sep 26

Excellent service and made to feelvery comfortable.

Tracey Edwards - Red Ox

14:33 08 Sep 26

Great communication, well presented clinic, great location.Appointments conducted in a sensitive and appropriate manner, by friendly professional staff putting me at ease.Complimentary tea or coffee to take away, nice touch after a caffeine free morning!

Kathryn Scorza

10:03 08 Sep 26

The Natural Doctor offers very efficient, courteous service, with discretion and consideration for patients and an emphasis on preventing disease developing. My regular thermographic breast scans provide peace of mind, backed up with expert analysis and long experience. Treatments are based on well-researched natural supplements and other products and prescriptions, underpinned by allopathic medical qualifications.

Joanne Kehoe

16:02 05 Sep 26

This will be my 4th Thermogram check with The Natural Doctor and each time I'm made to feel welcome by the staff . This time I've also had a well woman blood test with a later consultation with Dr. Eccles.I trust Dr Eccles with my health so much so I've also taken my daughter for a blood test and consultation and he was absolutely amazing.He has explained more in a 45min consultation than the NHS have over a 2 year period.Excellent team keep up the good work.

Lynn Hannay

16:39 17 Aug 26

very professional and supportive. I was immediately made me feel at ease and cared for .

Annie FIELD

16:14 14 Aug 26

Very efficient and slick procedure. I would certainly recommend the Natural Doctor

Donna Burgoyne

10:47 17 Apr 26

"This was my 4th time at the clinic for my annual thermogram. The atmosphere is very calming. I was met by Nazret who immediately put me at ease and explained the procedure..Once again the whole process was conducted very professionally and all questions I asked were either answered either immediately or also emailed later to me.I highly recommend an appointment for piece of mind."

Zion4

14:57 09 Apr 26

Having attended The Natural Doctor's Clinic on 3 occasions over the past few years for Breast Thermography Screening, followed by consultations with Dr Eccles, I wholeheartedly recommend this great service for women.If, like myself, you prefer to use an alternative to Mammography for breast screening, Thermography is a great, non-invasive, pain-free method of identifying early on any areas of potential concern. My experiences with the Clinic have all been very positive. The pre and post-appointment communication is very thorough and helpful. The clinicians that carry out the screening have been personable, kind, attentive women, who put you at ease during the procedure. And with Dr Eccles you are in safe hands; he is approachable, amicable whilst highly professional; he clearly cares about his patients and getting the best outcomes for you, using natural therapies and supplementation, and I thoroughly endorse his Thermography service.

Maureen Mcgachan

12:20 26 Feb 26

I had my first thermocheck with Nazret on the 18th Feb 2026.I was made very welcome at the clinic , Nazret was very patient with me as I was a bit nervous and unorganized! She was professional, helpful and knowledgeable.

Tracey Edwards - Red Ox

16:10 17 Jan 26

Excellent communication, professional and polite staff, well presented clinic, great location.Appointments conducted in a sensitive and appropriate manner, putting me at ease.Very well looked after and all enquiries dealt with swiftly and efficiently.Highly recommend!

Lynn Hannay

17:31 21 Nov 25

very professional and supportive. Michelle immediately made me feel at ease .

Julie Berry

17:01 17 Nov 25

Just been for my annual breast thermography at the Natural Doctor. Always a delight - the technicians that do the scans are all lovely and you know you are in safe hands. Such. a good way to take care of your breast health - non-invasive and picks up any problems in plenty of time to put things right before they get serious. Highly recommended.

Claire

18:14 14 Nov 25

Honestly it feels strange to say this, but it was such a lovely experience from beginning to end!I was looked after my the lovely and incredibly tentative Nazaret (apologies if I have spelt this incorrect) after experiencing breast appointments elsewhere which have left me wary, it’s safe to say that today restored my confidence and I took great comfort knowing this service is so well thought out and accessible to all 💫⭐️✨🌟Thank youClaire 😊

Sian Bristow

22:17 24 Oct 25

Very relaxed and comfortable atmosphere which puts you at ease. Staff are are very helpful and if unable to answer any questions they will find out and email the answer.

Caroline Collier

15:34 29 Sep 25

Very professional and would thoroughly recommend. Katia explained the process really clearly.

Marina Helenius-Beal

11:15 26 Sep 25

Thank you so much to Katia at The Natural Doctor for her outstanding service during my thermo scan. I couldn’t have been treated any better, she was professional, kind, and made the whole experience so comfortable. I would highly recommend Dr. Eccles and The Natural Doctor team to anyone looking for expert, compassionate care.

Fiona Whitby

19:30 11 Sep 25

I attended the clinic today to have a thermogram breast scan.I was welcomed by reception. I arrived ahead of my scheduled appointment and was happy to be seen earlier than expected.The technician was lovely and made me feel at ease throughout the procedure

Sonia Brown

11:38 11 Aug 25

Thank you so much for offering so much education and insight as part of the process. The scanning technician was so so so lovely. Every step of the process was fully explained. Looking forward to getting the report and using this as part of a proactive way of looking after my health.

Mayellen Phelan

06:47 09 Aug 25

I booked in to have my repeat follow up breast thermography scan, as always I was met by a lovely female scan technician who immediately put me at ease and answered any questions I had thoroughly and sensitively. I thoroughly recommend Dr Eccles and his team for anyone wanting to have a painless, safe and accurate alternative to a mammogram.

Tatina Semprini

00:49 18 Apr 25

I've been having these thermal breast scans (breast thermography) since 2008. It's a quick and easy treatment as well as comfortable and non-invasive, and it gives me peace of mind knowing it's safe and has no bad side effects like radiation. I also like to be proactive and know what's happening in my body on a regular basis so I can deal with it promptly if necessary. The staff has always been very friendly and helpful, so the whole experience is a pleasant one.

Nicola Barnes

20:15 29 Nov 24

The scan technician was really friendly and put me at ease. She was very knowledgeable about thermography and about the other treatments on offer at the Natural Doctor. I would definitely recommend the treatment.

Julia S

14:08 27 Nov 24

Great quality vitamins that are always delivered in a timely fashion! The staff at The Natural Doctor are always very friendly and helpful.

Joanne Kehoe

11:07 28 Oct 24

After suffering Breast Cancer 6 years ago I knew I had to be in charge of my own breast health .So after searching I found Dr . Eccles and he's changed my whole life approach to breast health .I now feel reassured and can get on with my life knowing I'm doing everything I can to stay healthy .I highly recommend Dr.Eccles and his team . They make you feel really comfortable throughout.

Sonia Rossi

22:12 22 Apr 24

Absolutely great service, been going for a number of years now, for the thermographic breast imaging. Staff is very professional and very kind and observant at the same time. Results come through within a couple of days.Would continue to use this service as an alternative to mammogram, for as long as the clinic is there.

Catherine Hancox

11:31 16 Mar 24

I have found all the staff to be helpful and understanding.A pleasure to deal with.My consultation with Dr Eccles was not only informative medically speaking, but he also tried so hard to find a solution to my problems. At the end of the consultation, I felt much calmer. I really felt as if he were 'routing' for me. I am most grateful.

Julie Berry

15:44 06 Oct 23

Always a delight to pay a visit to the Natural Doctor. He's currently the only doctor I trust. Genuinely concerned with people's health. I've been having regular thermal scans for years, having been pegged as 'at risk' for breast cancer. All the ladies that do the scans are lovely and you know you are in safe hands with his advice on how to put things right if they look a bit dodgy - the scans pick up any problems way in advance of anything serious. A no-brainer for me.

Muxloe Property

19:48 17 Jun 22

The Dr helped me feel like myself again after lots of low level symptoms. My GP dismissed me. It was worth every penny. Thank you

Janie Wolf

09:06 31 May 22

Dr Eccles has given me my life back, because he has balanced my hormones in a way that enables me to live my life to the full again!I was not only suffering with menopause fatigue and the many other symptoms of menopause, but I had ongoing lethargy with Auto-Immune Hashimotos and a struggling thyroid. It came to the point I didn’t know which symptom was due to which hormone deficiency.After my second thorough consultation with Dr Eccles, he had tweaked my dose and found I was indeed Iodine deficient. Now I am beginning to have normal levels of energy again and it is getting better and better, for the first time in five years! I sleep like a baby and my overactive bladder has been calmed. I am so glad I found Dr Eccles, life is too short to suffer with debilitating symptoms, he is the best doctor for me!

Nicky Emlick

21:19 23 Feb 22

Highly recommend this practice. My experience so far after taking the thermogenic breast scan, and Bio identical hormone replacements has been a very pleasant and informative process.

Crazy T

10:06 27 Oct 21

I started seeing Dr Eccles almost 3 years ago for fertility issue , after struggling for 9 years and 2 miscarriages 2 years a part .I had done blood test with them and was on natural hormonal medication for almost 2 years ,and it worked for me and i fell pregnant and i have a 5 month old son now .I am still seeing him for general health and hopefully working towards second pregnancy.He is amazing , listens to every concern and answer all queries very nicely and in friendly manner and girls at receptions are also great and quick at responding to any questions or concerns i might have.

Kelly Hafner

15:58 09 Sep 21

I began to see Dr Eccles six years ago and he continues to provide excellent care and attention every time I see him. I have referred several friends to him and they have all been very happy. Both Dr Eccles and his staff genuinely care and always go the extra mile. I highly recommend him for all areas of female health, immunity and healthy ageing in general!

Victoria Harris

09:54 12 Aug 20

A very friendly but professional service. Experts in their field that go over and above to ensure you have the best service and experience.Highly recommend.

Alison Kittle

14:33 14 Aug 19

Been visiting this clinic for nearly 10 years. It reassures me about my breast health and if I raise any concerns they are always answered well. Staff are professional but friendly. Dr Eccles knows his field. Will keep returning for my check ups. Peace of mind is worth so much.

maria

13:27 16 Jul 19

For several years I have been seeing Dc Eccles for general l wellbeing. After I started seeing him, I felt much better. Excellent Doctor with very good supplements and product. I highly recommend Dr Eccles and his prescription.

Anwen Pragnell

14:50 20 Jun 19

A recent breast health scare in my 30's lead me to seek a less invasive option to check breast health. The Thermocheck scan, detailed report and Skype consultation with Dr Eccles was very professional and reassuring. I now feel more informed and supported in preparation for my hospital appointment. I highly recommend Dr Eccles and his team to provide an efficient, professional service and support your health naturally.

Arthur Moore

09:27 16 Jan 18

Thank you for giving me the opportunity to use your excellent product. Although it has only been 2 weeks, both myself and my wife have noticed, the hair growth has certainly become thicker, more of a covering. This is very encouraging, following many years of not really being bothered about my hair loss, now that I am noticing an improvement I am very excited at the prospects of once again having a full head of hair.

See All Reviews

Bioidentical Hormone Replacement Therapy for Women - Precision Menopause Treatment, Harley Street

Request a call back

Feel Like Yourself Again – and Age More Slowly While You Do

What Is Bioidentical Hormone Replacement Therapy?

How is BHRT different from HRT?

Hormones and Longevity – The Connection Most Clinicians Don’t Discuss

Real Results from Real Women

Choose the Right Level of Support for You

Essential Menopause Programme: Standard BHRT

Comprehensive Menopause: Complete BHRT & Functional Medicine

How It Works – Your Journey with Us

How much does BHRT cost?

Essential Menopause Programme: Standard BHRT

Comprehensive Menopause Programme: Complete BHRT

Your Clinical Team

Want to learn more about the science behind BHRT?

BHRT FAQs

Is this the same as standard HRT?

What is compounded medicine?

Is BHRT safe?

What symptoms might indicate I need BHRT?

Do I need a GP referral?

Can I be treated outside the UK?

Take the First Step Towards Better Ageing

Get in touch with us

NAVIGATE

FOLLOW US

SUBSCRIBE NOW